Adenosine has been implicated in the spontaneous and abrupt arrest of seizures (Dragunow, 1986). The anticonvulsant action of adenosine and its analogs has been observed in several different studie...
The present work investigates the effect of rats pretreatment with the purinergic agonists ADO, 2-CADO, CPA and CPCA on the forebrain levels of the neurotransmitters glutamate and GABA in rats afte...
DMSO is also widely utilized in the storage of human and animal cell lines and bacteriophage, as a cryoprotective agent.Previous studies reported that DMSO reduces inflammation by several mechanism...
Many studies have gone on to suggest that vitamin D deficiency is a contributing factor in the pathogenesis of ulcerative colitis (UC). Adhesion molecules e.g. intracellular adhesion molecule (ICAM...
Arginase (AR)enzyme is implicated in many studies in pathogenesis of IBD.E-selectin , an adhesion molecule, plays an important role in migration of leucocytes into the colonic mucosa.Many studies h...
The characteristic pathologic feature of UC is infiltration of the intestine by mononuclear cells, predominantly lymphocytes. Current research is directed to Vitamin D and its role in the disease a...
Rolipram is a phosphodiesterase-4 (PDE 4) inhibitor. It is being researched as a possible alternative to current antidepressants (Washtel, 1983; Bobon et al., 1988). Recent studies show that rolipr...
SNP,a nitric oxide (NO) donor is a common medication used to affect peripheral vasodilation in arterioles and venules. SNP is often administered intravenously to patients who are experiencing a hyp...